holby city It has been on air after almost 23 years.
The hit medical drama will end next March, the BBC has announced.
The broadcaster said it has decided to bring Holby closer “to make room for new opportunities that better reflect, represent and serve all parts of the country”.
A BBC statement read: “We are incredibly proud of Holby City but it is with great sadness that we are announcing that after 23 years, the show will end on screens in March next year.
“We sometimes have to make difficult decisions to make room for new opportunities and as part of the BBC’s commitment to creating more shows across the UK, we have adapted the show to reshape the BBC’s drama slate. To better reflect, represent and serve all parts of the country.
“We would like to take this opportunity to thank the wonderful team at BBC Studios and all the cast and crew involved in the show since 1999.”
The spokesperson continued: “Holby has been a legend with audiences, delighting millions of viewers each week and winning hundreds of awards with a compelling mix of cutting-edge medical stories and explosive personal stories.
We look forward to working with the team over the coming months to ensure that when this is finished, Holby leaves at a high level.