NFL odds, lines, points spreads: Updated betting information in week 4 to select each game

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Week 3 of the 2021 NFL season once again belonged to the underdogs. The Underdogs went 9-7 against the span for the second week in a row to improve their record of the year to 30-18, a coverage rate of 62.5.

That said, the trend is likely to level off and stay around .500 as the year goes on. Bettors and bookmakers learn a lot more about each team, and as they gather more data, it becomes easier to find undervalued lines and make dormant choices against the spread.

Three games is a pretty solid sample size for determining trends. Skilled players bet a lot on separating the good and bad teams from the lucky and unlucky ones. Some teams look good but have played a weak schedule. Others look bad but have lost several one-possession battles late. Knowing the difference between good and lucky can make a huge difference when making weekly choices against the spread.

Injury has also changed the betting landscape. There have been plenty of teams that have lost quarterbacks, including Tua Tagovailoa (Dolphins), Andy Dalton (Bears) and Tyrod Taylor (Texans). Other teams, such as the Colts and Eagles, are dealing with significant injuries to non-quarterbacks. It makes it harder for them to play at a high level.

All this information is useful for the players. This may explain why lines change and why some teams do not live up to expectations. Knowing the latest trends, odds and news on injuries is critical, so be sure to be aware of everything when week 4 of the 2021 NFL season begins.

For more expert NFL predictions, check out Sporting News’ selection right up and against the spread in Week 4.

WEEK 4 NFL PICKS: Against the Spread | Straight up

NFL odds for week 4

Below are the latest NFL odds in Week 4, including point spreads, money lines, and over-totals for each game, according to the FanDuel Sportsbook.

Last updated: Wednesday, September 29th

NFL points spread week 4

Game Dispersion
Jacksonville Jaguars at the Cincinnati Bengals CIN -7.5
Washington football team of the Atlanta Falcons VAR -1.5
Detroit Lions and Chicago Bears CHI -3
Tennessee Titans on New York Jets TEN -7.5
Cleveland Browns of the Minnesota Vikings CLE -2.5
Indianapolis Colts at the Miami Dolphins MIA -1.5
Carolina Panthers of the Dallas Cowboys FROM -4.5
New York Giants and New Orleans Saints NO -7.5
Kansas City Chiefs and Philadelphia Eagles KC -7.5
Houston Texans at Buffalo Bills BUF -16.5
Arizona Cardinals and Los Angeles Rams LAR -4.5
Seattle Seahawks and San Francisco 49ers SF -3
Baltimore Ravens and Denver Broncos THE 1ST
Pittsburgh Steelers at the Green Bay Packers GB -7
Tampa Bay Buccaneers at New England Patriots TB -7
Las Vegas Raiders on the Los Angeles Chargers LAC -3.5

MORE: Why the Patriots have zero chance of beating Tom Brady, Buccaneers in rematch

NFL Money Lines Week 4

Game Moneyline
Jacksonville Jaguars at the Cincinnati Bengals CIN -330
Washington football team of the Atlanta Falcons VAR -118
Detroit Lions and Chicago Bears CHI -152
Tennessee Titans on New York Jets TEN -360
Cleveland Browns of the Minnesota Vikings CLE -130
Indianapolis Colts at the Miami Dolphins MIA -132
Carolina Panthers of the Dallas Cowboys FRA -230
New York Giants and New Orleans Saints NR -360
Kansas City Chiefs and Philadelphia Eagles KC -335
Houston Texans at Buffalo Bills BUF -1200
Arizona Cardinals and Los Angeles Rams LAR -210
Seattle Seahawks and San Francisco 49ers SF -156
Baltimore Ravens and Denver Broncos DEN -116
Pittsburgh Steelers at the Green Bay Packers GB -295
Tampa Bay Buccaneers at New England Patriots TB -290
Las Vegas Raiders on the Los Angeles Chargers LAC -184

NFL over-unders Week 4

Game Over under
Jacksonville Jaguars at the Cincinnati Bengals 46.5
Washington football team of the Atlanta Falcons 48.5
Detroit Lions and Chicago Bears 42.5
Tennessee Titans on New York Jets 46
Cleveland Browns of the Minnesota Vikings 53.5
Indianapolis Colts at the Miami Dolphins 43.5
Carolina Panthers of the Dallas Cowboys 50.5
New York Giants and New Orleans Saints 43.5
Kansas City Chiefs and Philadelphia Eagles 54.5
Houston Texans at Buffalo Bills 48
Arizona Cardinals and Los Angeles Rams 54.5
Seattle Seahawks and San Francisco 49ers 52.5
Baltimore Ravens and Denver Broncos 44.5
Pittsburgh Steelers at the Green Bay Packers 45.5
Tampa Bay Buccaneers at New England Patriots 49.5
Las Vegas Raiders on the Los Angeles Chargers 52.5

NFL POWER RANKINGS: Rams on the way up after victory over the Bucs

NFL best game in week 4

Aries (-4.5) vs. Cardinals

The Rams have proven to be one of the best NFL teams so far in 2021, and they have a good chance of remaining as the last undefeated standings in the not-so-distant future. Their match in week 4 with the Cardinals might look tough on paper, but recent history favors the rams in this one.

Los Angeles has never lost to Arizona during Sean McVay’s time as coach of the Rams. He has an 8-0 record against Arizona, and the Rams have won those games by an average of 20 points. Only one of the matches was decided by less than 10 points.

It is worth noting that Kyler Murray was only the Cardinals’ starting quarterback in four of those games, but his numbers have still been poor against the Rams defense. He has recorded an accomplishment percentage of 58.7 against the Rams and has generated six total touchdowns relative to seven revenue.

Brandon Staley may be gone, but Raheem Morris has proven to be capable of getting his defense to perform in key positions. He should find a way to keep Murray out of balance. Murray has thrown four interceptions through three games this season so he can make some mistakes against the Rams’ strong secondary.

After all, we saw what the rams did to Tom Brady and the Buccaneers last week. The defense limited Tampa Bay to 17 points before the Bucs made things respectable with a waste time touchdown in the Rams’ 34-24 victory.

On the other side of the ball, the Rams’ offense is averaging 304.3 passing yards per game. Match, good for the sixth most in the NFL. The Cardinals have been solid against the pass this year, but they may have trouble slowing down the Rams’ arsenal. They simply do not have the corner depth needed to cover e.g. Cooper Coup, Robert Woods, Van Jefferson and a seemingly rejuvenated DeSean Jackson.

The Aries can win this by a touchdown; given their history, they should. You can count on them as favorites this week, even if they face another undefeated team.

Chiefs (-7.5) at the Eagles

Chiefs have not been credible against the spread of late. In fact, since the start of the 2020 season, they have only been 8-14 and they are 0-3 ATS this year. They also have the second-lowest coverage rate in the NFL (36.4) in this range. Only the Jets (31.6) are worse.

That said, Kansas City should be hyper-motivated to win their Week 4 competition. They sit at 1-2 on the season and are in last place in the AFC West. They are guaranteed to stay there for another week, but they need to start thinking about catching the Raiders and Broncos, who are both 3-0.

The Eagles will give the Chiefs a good chance of winning. Philadelphia just struggled tremendously to stop the Cowboys’ offense. The Cowboys run the ball better than the Chiefs, but Clyde Edwards-Helaire should be able to take advantage of the Eagles ’26. ranked run defense that allows 133.7 rushing yards per. Match.

Oh yes, Chiefs also have Patrick Mahomes. Mahomes has lost back-to-back fights just twice in his career. What has he done after the two-game losing streaks? He has helped the Chiefs win an average of 28 points per game. Match. That includes a 32-point victory over the Raiders in 2018 and a 24-point victory over the Broncos in 2019.

The Eagles may be able to run the ball a bit on the Chiefs, who battled Lamar Jackson earlier in the season and have the NFL’s second worst running defense, but will they be able to do enough if the Mahomes and Chiefs shred the Eagles’ defense like Dallas did? The Cowboys scored just 41 points on them so the Chiefs could do the same.

At the end of the day, this seems like a good recurring theme for Chiefs. We are willing to trust them after we faded them against the chargers last week.

MORE: Inside Justin Tucker’s record-breaking field goal

Texans (+16.5) on Bills

I know what you’re thinking. The Texans are not a good team and they are going to start Davis Mills in just their second career NFL game. The Bills have won their last two games by 22 and 35 points respectively.

So why should you choose Texans? It all has to do with history and motivation.

Since 2003, teams that are 14-point underdogs or higher have recorded a record of 70-61-4 against the spread per game. TeamRankings.com. This means that the favorite has covered 45.1 percent of the time, while the underdog has covered 51.9 percent of the time. That’s a solid advantage for the underdog.

What can we take from this? It’s simply hard for a favorite to cover a spread of two touchdowns or more. As such, it is usually better to go with the underdog as all it may require is a waste time touchdown or fluky turnover from the favorite to earn a cover.

The Bills are also a good team to fade here given their upcoming schedule. They play Chiefs at Arrowhead Stadium in Week 5, so they might be looking forward to that AFC Championship Game rematch. If they overlook the Texans a bit, it could give Houston a chance to stay in the game longer and prevent the bills from pulling out directly.

The Texans also have a resting advantage when they last played on “Thursday Night Football” in Week 3. So they get a little fresher than the Bills.

Buffalo will almost certainly win this game. -1200 money line implies that they have a 92.3 percent chance of doing so. But don’t be surprised if the Texans prevent it from getting out of hand and covering this 16.5-point spread.

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